Unexpectedly, the proportion of IgM BCR transcripts was significantly increased in ME/CFSmm patients compared to the other groups (Figure 4F) (ME/CFSmm vs. HC p = 0.04, ME/CFSmm vs. MS p = 0.008), although this analysis was not part of the original hypotheses we set out to test. This evidence concerns the gene CD40LG and myeloid sarcoma.