In this study, we present a potential candidate for a novel blood biomarker of sarcopenia - FOXO3A. Furthermore, we detected upregulation of the mRNA levels of important epigenetic enzymes, DNMT3A and SIRT3, in the whole blood of healthy controls over 50 years old, compared to healthy controls 25 to 30 years old. This evidence concerns the gene FOXO3 and sarcopenia.