KLRC2 and myeloid sarcoma: Accordingly, pwMS have increased NKG2C expression in NK cells compared to healthy donors, with the highest expression in the CMV-seropositive pwMS compared to CMV-seronegative pwMS, suggesting that CMV could promote NKG2C expression in NK cells, although the mechanism involved or the impact over NK cell function and MS pathogenesis are currently unknown (184).