Age: Participants aged between 30 and 70 years; Type 2 Diabetes: Participants with type 2 diabetes who were more than 20% over their ideal body weight based on Metropolitan Life Insurance norms; Medication: Participants not currently receiving insulin therapy; Fasting Plasma Glucose (FPG): Participants with FPG levels of less than 16.7 mmol/L after discontinuing oral diabetes medications. The gene discussed is INS; the disease is diabetes mellitus.