The impact of BSEP on ACh production is illustrated in Fig. 8D. The ACh levels were as follows: normal group: 1.5 ± 0.0 nmoL/μL, sham group: 1.4 ± 0.1 nmoL/μL, AD control group: 1.1 ± 0.1 nmoL/μL, BSEP (400): 1.2 ± 0.0 nmoL/μL, BSEP (200): 1.1 ± 0.0 nmoL/μL, donepezil: 15.2 ± 0.1 nmoL/μL, SFN (10): 1.2 ± 0.1 nmoL/μL. Here, ABCB11 is linked to Alzheimer disease.