SFN and Alzheimer disease: The sham group (1374.7 ± 170.39 mU/mL: 131 %), BSEP (400) (1454.76 ± 63.01 mU/mL: 137 %), BSEP (200) (1006.54 ± 39.84 mU/mL: 95 %), donepezil (1248.51 ± 138.72 mU/mL: 117 %), and SFN (10) (1104.65 ± 123.41 mU/mL: 105 %) exhibited AChE activity suppression levels similar to or lower than that of the normal group compared to the AD control group.