Fibrosis and HCC: Our RNAseq analysis of the livers from Efcab4b−/− mice exhibit downregulation of the macrophage marker CD163, the CD44 antigen and Lymphocyte antigen 96 (Ly96) and upregulation of beta-1, 4-galactosyltransferase 1 (B4GALT1). Here, B4GALT4 is linked to hepatocellular carcinoma.