In another study, ectopic endometrial stromal cells showed increased levels of NOD1 expression and interleukin-8, while the NOD1 inhibitor ML-130 suppressed proliferation, clonal expansion, invasion, and migration of these cells without impacting apoptosis (23).The pathophysiological mechanism behind diminished ovarian reserve in endometriosis remains unclear. Here, CXCL8 is linked to endometriosis.