INS and type 2 diabetes mellitus: 1. ImP levels significantly correlated with diastolic blood pressure (rs = 0.285, P = 0.004) and showed borderline significance with systolic blood pressure (rs = 0.187, adjusted P = 0.060) and LDL-cholesterol (rs = −0.181, adjusted P = 0.064);2. Among overweight/obese non-T2D subjects, plasma ImP concentrations do not significantly differ between insulin-sensitive and insulin-resistant individuals (16.3 nM vs. 19 nM).