After immunohistological examination of the resected specimen from the right atrium, we conducted FISH for CDKN2A/p16 (indicated by red immunofluorescence) and chromosome 9 centromere (indicated by green immunofluorescence).4)Figure 3F shows homozygous loss of CDKN2A/p16, suggestive of mesothelioma. Here, CDKN2A is linked to mesothelioma.