CD47 and colorectal carcinoma: Microporous Prussian blue nanoparticles (MPBNPs) serve as both photothermal sensitizers and drug carriers, loaded with 3-bromopyruvate (3BP) in their cavity and coated with genetically programmable cell membranes overexpressing MSIRPα (CM-MSIRPα) to synchronously target colorectal cancer (CRC) cells and enhance macrophage phagocytosis of CRC cells by competitively blocking the SIPα-CD47 interaction.