Even after adjustment for age, sex, presence of diabetes mellitus, prior peripheral- or coronary artery disease, prior MI, prior cancer, left-ventricular ejection fraction, kidney function and c-reactive protein, a non-implementation of a rhythm control in FDAF patients remained an independent predictor for all-cause mortality with an adjusted HR (aHR) of 1.52 (95%CI: 1.14–2.04), p = 0.0043. This evidence concerns the gene CRP and myocardial infarction.