Cross-sectional analysis of T cells in both HD and CLL PBMCs revealed strong co-localization between BodipyTM493/503 and PLIN2 in HD T cells (Fig. 4C, Supplementary Fig. 4E), particularly in stimulated samples, indicating that all lipid aggregates in these cells were lipid droplets (PLIN2+). Here, PLIN2 is linked to Huntington disease.