FAM171B and type 2 diabetes mellitus: Using this approach, we found 11 with nominal evidence (p-value < 0.05) that the BMI exposure (3 proteins), the protein exposure (7 proteins), or both (1 protein) lead to T2D risk, with one, FAM171B, significant after a multiple testing correction (FDR p-value < 0.05; see Supplementary Fig. 17B and C).