PRTN3 and tuberculosis: Mycobacterium tuberculosis (Mtb), a highly virulent bacterial pathogen, isresponsible for approximately10.6 million new cases of tuberculosis (TB) and 1.3 million deathsannually.3Mtb utilizescarboxymycobactin (cMbT) and/or mycobactin (MbT) to scavenge Fe3+ ions from host cells,4 particularlywithin the phagosome of lung macrophages (Figure 1A).