Additionally, subgroup analyses indicated that serum SP-D could act as a predictive factor for mortality among patients with ILD (HR=1.001, 95%CI= 1.000, 1.002, p=0.030) and idiopathic interstitial pneumonia (HR=1.011, 95%CI= 1.002, 1.020, p=0.016), but not for poor prognosis in IPF (HR=1.003, 95%CI= 1.000, 1.006, p=0.087) (Figure 9). The gene discussed is SFTPD; the disease is idiopathic pulmonary fibrosis.