CRP and juvenile polyposis syndrome: While C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) are commonly recommended blood inflammation markers for diagnosing periprosthetic joint infection (PJI) according to several PJI diagnosis guidelines [1,2,3,4,5], their performance may be suboptimal in certain situations, such as in cases of low-grade virulence or chronic PJI [6].