Then, we found that AUC of combined CRP and CPR, combined CRP and FIB, combined CRP and CDR, combined CRP and CFR, combined ESR and fibrinogen in PJI diagnosis were similar with combined CRP and ESR in PJI diagnosis, combined CRP and CPR, combined CRP and FIB, combined CRP and CDR, combined CRP and CFR, combined ESR and fibrinogen can be used as for PJI diagnosis. This evidence concerns the gene CRP and juvenile polyposis syndrome.