Studies have shown that knockdown CSNK2A1 expression in KRAS-mutant lung cancer cells inhibits cancer cell proliferation and Wnt/β-catenin signalling (Wang et al., 2019); Yu et al. used machine learning algorithms to screen genes related to mitochondrial autophagy in NSCLC and established a prediction model that includes CSNK2A1 (Yu et al., 2023). This evidence concerns the gene KRAS and lung cancer.