By silencing circEPSTI1 and targeting the miR-375/409-3P/515-5p-SLC7A11 pathway, the study succeeded in reducing the relative ratio of glutathione to reduced glutathione in cervical cancer cells through a competing endogenous RNA-mediated manner, significantly reduced the ratio of glutathione to GSSG in cervical cancer cells, and inhibited the expression of GPX4 protein. Here, SLC7A11 is linked to cervical carcinoma.