Here, we found that in vivo immunoblot analyses confirm increased levels of p-FAK in the Myh11R247C/R247C aortas at baseline (Figure 2C), and levels of p-FAK increase further after two weeks of HTN induction in Myh11R247C/R247C aortas but not in WT aortas (Figure 2D). Here, PTK2 is linked to hypertensive disorder.