In support, a survival analysis from the TCGA database indicated that elevated TGFβ3, GLI2, and YAP1 mRNA levels significantly correlated with an OS rate in bladder cancer patients (p < 0.05), high GLI2 expression decreased the outcome the most with HR of 1.68, TGFβ3 and YAP1 exhibited the HRs of 1.54 and 1.51, respectively (Fig. 1D). This evidence concerns the gene YAP1 and urinary bladder cancer.