Khalifa et al., following an RCT on women with endometriosis-related infertility, concluded that gonadotropin-releasing hormone agonists (GnRH) and dienogest, a fourth-generation selective progestin pretreatment, improved ovarian stimulation/number of mature oocytes (6.6 ± 1.3 vs. 6 ± 1.8, p = 0.71), number of transferable embryos (4.5 ± 1.8 vs. 5.1 ± 2.0, p = 0.63), pregnancy rates (22.39% vs. 25.37%, p = 0.69), and clinical pregnancy rates (17.91% vs. 25.37%, p = 0.29) without any significant difference among the groups [52]. Here, GNRH1 is linked to endometriosis.