SBP, systolic blood pressure; DBP, diastolic blood pressure; BMI, body mass index; CHA2DS2-VA, congestive heart failure, hypertension, age ≥75 years, diabetes mellitus, prior stroke, vascular disease, age 65-74 years; HF/LVEF, heart failure/left ventricular ejection fraction; SGLT2, sodium-glucose cotransporter-2 inhibitors. The gene discussed is SLC5A2; the disease is diabetes mellitus.