TG and neoplasm: The study of factors predictive of the occurrence of metastases showed that age ≥ 55 years, male gender, follicular histological type, extra-thyroidal extension, vascular invasion, tumor size > 4 cm, detectable thyroglobulin level, disease stages (≥II), high risk of relapse, and the presence of cardiovascular comorbidities were associated with the occurrence of metastases.