Furthermore, NFKB-GS scores are significantly higher in advanced-stage tumors than in early-stage ones (Figure 5E; Supplementary Figure S4F) and are associated with poor survival in bladder cancer patients (Figure 4F; Supplementary Figure S4G), confirming that NFKB is associated with tumor aggressiveness in bladder cancer. Here, NFKB1 is linked to neoplasm.