Upstream, transcription from miR-29b/c is reported to be primarily suppressed by either MYC or NFKB transcription factor (Chang et al., 2008; Wang et al., 2008), which we sorted out to be NFKB in the case of bladder cancer, as NFKB-related, but not MYC-related, gene sets are enriched in advanced-stage, aggressive tumors in bladder cancer patients (Figure 5; Supplementary Figure S5). The gene discussed is MYC; the disease is urinary bladder cancer.