NFKB1 and urinary bladder neoplasm: To this end, we performed GSEAs using gene sets related to transcriptional profiles of these TFs and found that NFKB-related gene signatures (NFKB-GS) (Figure 5B; Supplementary Figure S4A), but not those of MYC (Supplementary Figures S4B, C), are enriched in aggressive bladder tumors.