Moreover, in aclosed-chest acute murine MI/R model, CCL11 protein levels, one of theCD4+ T cell-associated chemokines, was elevated on day 7 and at day 14 in hearttissues but lower on day 14 compared with day 7, suggesting that CCL11 mightparticipate in the cardiac repairing and remodeling after AMI/R [88]. The gene discussed is CCL11; the disease is myocardial infarction.