However, CCL27, BMP7, ANGPTL4, FGFR1, MLN, MSMP, SVEP1, RFK, HEXIM2, VAT1, ALDH2, and COMT may not have shared causal variants in the same region associated with T2DM (PPH3 + PPH4 < 0.8). This evidence concerns the gene VAT1 and type 2 diabetes mellitus.