The extant literature and reports have demonstrated that PD is characterized by a number of factors, including oxidative stress [85–87], calcium homeostatic imbalance [88–90], abnormal accumulation of alpha synuclein [91,92], impaired mitochondrial function [93–95], endoplasmic reticulum stress [96–98], intestinal flora dysbiosis [99,100], intestinal flora dysregulation, and many other factors. This evidence concerns the gene SNCA and Parkinson disease.