IL6 and viral pneumonia: Further supporting this, preclinical models of severe viral pneumonia and pulmonary inflammation have shown that S1P signaling through S1P1 can reduce inflammation by repressing the over‐recruitment of immune cells, interfering with specific cytokine release, including C–C motif ligand 2 (CCL2) and interleukin (IL)‐6, and maintaining the lung endothelial barrier integrity.6, 7, 8