However, median concentration of uNGAL and TIMP-2*IGFBP7 at first collection (DOL 1–3) were significantly lower in preterm infants without AKI than in healthy full-term infants (uNGAL 10.0 vs. 41.4 ng/ml, p = 0.007; TIMP-2*IGFBP7 0.05 vs. 0.22 (ng/ml)2/1000, p < 0.0001) (Fig. 1). The gene discussed is IGFBP7; the disease is acute kidney injury.