CRP and infectious meningitis: In the era of evidence-based medicine, further description of the evidence for the value of PCT testing in the febrile pediatric emergency population may contribute to its use in clinical practice Although several systematic reviews have been performed on the use of PCT in febrile children, they either did not separately analyze SBI (e.g. pneumonia, urinary tract infection)) and IBI (e.g. sepsis, meningitis) [1] or did not compare PCT to CRP directly [2].