In addition, the results of laboratory data showed that the levels of C-reactive protein (CRP), creatinine kinase-myocardial infarction (CK-MB), Fibrinogen, Brain Natriuretic Peptide (BNP) and high-density lipoprotein (HDL) were significantly higher in MINOCA group compared to MIOCA (SMD= −0.01; 95%CI= −0.08, 0.1, SMD= −0.25; 95%CI=−0.16, 0.35, SMD= −0.42; 95%CI= −0.26, 0.58, SMD= −0.42; 95%CI= −0.14, 0.71, SMD= −0.25 ; 95%CI= −0.38, −0.12, respectively). This evidence concerns the gene NPPB and myocardial infarction.