Interestingly, however, while investigating the effect of dapagliflozin and magnesium supplementation on renal magnesium handling factors—including the TRPM6 channel—in the context of metabolic syndrome—here mimicked by high-fructose diets, Ng et al. also performed TRPM6 immunohistochemistry of male Sprague-Dawley rat sections (Ng et al. 2021). The gene discussed is TRPM6; the disease is metabolic syndrome.