NLRP3 and infection: Furthermore, genes associated with inflammaging (IFNα, IL1β, NLRP3, IL6, IL1R and p16) and myeloid lineage (RUNX1, Fil1, CD150, PU.1 and GM-CSF) genes that were upregulated by Omicron PsV infection were downregulated by NGO treatment (Fig. 5c, d).