We then subjected Neo-2/15-stimulated BBζ to the inhibitor targeting STAT1 (Fludarabine), STAT3 (NSC74859), STAT5 (Stafia1), STAT1/3/5 (Nifuroxazide), Akt (AZD5363), mTOR (Rapamycin) or c-Myc (10058-F4) prior to co-culture with three MSLN positive tumor cell lines, and the results showed that the cytolytic activity of Neo-2/15-stimulated BBζ was nearly abolished by c-Myc inhibitor or dual inhibitions of STAT5 and Akt or STAT5 and mTOR (Fig. 3d). The gene discussed is MYC; the disease is neoplasm.