TMEM86B and COVID-19: The proposed involvement of TMEM86A in severe acute respiratory syndrome coronavirus 2 resistance (6), protein kinase A–dependent energy metabolism (5), sterol-dependent membrane remodeling in macrophages (7), and keratinocyte differentiation (17) suggests that we may learn new roles for lysoplasmalogens and their degradation by TMEM86A and TMEM86B.