Unfortunately, however, this study did not assess the effects of GLP-1R agonism alone [1081], which seems crucial given that some studies show GLP-1R agonism to exhibit neuroprotective effects in patients with AD or PD [[1082], [1083], [1084], [1085], [1086], [1087], [1088]]. This evidence concerns the gene GLP1R and Parkinson disease.