In line with a potential cardioprotective effect of GIP are small clinical studies showing that lower circulating levels of GIP are associated with higher mortality and worse CV outcome in high-risk patients with acute MI [862], and that serum levels of GIP are decreased in people with ST-elevation myocardial infarction (STEMI) relative to individuals without MI [863]. The gene discussed is GIP; the disease is ST Elevation Myocardial Infarction.