These findings suggest hyperglucagonemia as a potential therapeutic target in T1D.41 Fredheim et al42 studied a cohort of 129 Danish children (mean age ten years) with T1D over 60 months, finding that postprandial glucagon levels increased 160% from diagnosis and correlated with higher glucose levels and lower C-peptide levels. This evidence concerns the gene GCG and type 1 diabetes mellitus.