Extending the MR analysis to migraine subtypes, there was no evidence to suggest that plasma HIF‐1 levels were associated with the risk of MOA (OR = 0.931, 95% CI = 0.832−1.042, p = 0.214), MA (OR = 0.947, 95% CI = 0.861−1.042, p = 0.263), and MAD (OR = 0.893, 95% CI = 0.544−1.465, p = 0.653) (Figure 2). Here, HIF1A is linked to migraine disorder.