In second place, with 11 genes involved (eotaxin, GM-CSF, IL-1β, IL-4, IL-5, IL-6, IL-8, IL-13, IL-17, IP-10, MCP-1), is the “IL-17 signaling pathway” (FDR = 1.9 × 10–20), followed by pathways not directly linked with SDS but related to a chronic inflammatory condition (“inflammatory bowel disease” (Tavakoli et al. 2021) and “asthma” (Hammad and Lambrecht 2002)). The gene discussed is CXCL8; the disease is inflammatory bowel disease.