EGFR and psoriasis: This highlighted a series of immune pathways and gene sets whose membership is over-represented at psoriasis risk loci (1632 gene sets at false discovery rate <5%; Supplementary Fig. 11, Supplementary Data 14A); this includes protein-protein interaction subnetworks for the genes CBL (proto-oncogene), EGFR (epidermal growth factor receptor; EGFR signalling being regulated via Cbl39), ESX1 and TEC (Tec Protein Tyrosine Kinase) (Supplementary Data 14B) that are implicated for the first time in this study.