L-carnitine supplementation has shown promise in reducing oxidative stress markers, such as malondialdehyde and myeloperoxidase, in colitis models, which could mitigate tissue damage and inflammation in the colon.[41] In summary, the interaction between Clostridium S. felsineum and carnitine metabolism may contribute to UC by disrupting essential metabolic processes and exacerbating inflammation. Here, MPO is linked to colitis.