RICTOR and invasive breast carcinoma: Similarly, high Rictor protein expression assessed by RPPA correlated inversely with OS in invasive breast cancers (Fig. 1B), as did Rictor phosphorylation at T1135 (P-Rictor T1135; Supplementary Fig. S1A), a phospho-site correlating with, but not required for, oncogenic mTORC2 signaling (34).