Furthermore, the expression level of Ccl5 (RANTES) was increased in Hexa-/-Neu3-/- mice, similar to mouse models of the Niemann Pick type C (Npc1-/-), Gaucher (Gba-/-) and mucolipidosis type IV (Mcoln1-/-) (Cologna et al. 2014; Vitner et al. 2012; Cougnoux et al. 2019), and this increase was reduced after KD and PG treatments. This evidence concerns the gene GBA1 and mucolipidosis type IV.