Although ATB346 supplementation did not significantly decreased AAA incidence in AngII‐infused ApoE−/−;Senp3flox/flox mice (Figure 7G), it significantly decreased the incidence of aortic rupture (Figure 7H) in AngII‐infused ApoE−/−;Senp3flox/flox mice, suggesting that ATB346 supplementation improved AAA pathology in ApoE−/−;Senp3flox/flox mice to some extent. The gene discussed is APOE; the disease is triple-A syndrome.