AKT1 and neoplasm: This L‐lactate consumption from the inside out greatly reduces the L‐lactate level of tumor tissue, improves the tumor immunosuppressive microenvironment while reducing the adenosine triphosphate (ATP) supply, and can effectively inhibit the expression of PD‐L1 in tumor cells and the activation of the AKT‐mTOR metabolic pathway, thereby enhancing antitumor effect.