Additionally, as previously mentioned, the R1819W mutation in FASN can lead to cognitive impairments in patients who are diagnosed with AD.[23] Furthermore, in another study on AD patients, we found that some patients carry the V2005A point mutation in FASN.[35, 54] Although the significance of this mutation is not high due to the limited cohort size, it also suggests the possibility that FASN point mutations can cause cognitive impairments. Here, FASN is linked to Cognitive impairment.