Due to the limitation of ND patient samples, we could not analyze the expression and activity of FASN; the clinical evidence of the vital role of FASN‐mediated de novo fatty acid synthesis has been discovered in several large‐scale genetic variant studies in ND patients.[35, 36, 37, 38] The genetic variants of FASN showed a causal correlation with ND incidence, especially R1819W23 and A1089A37 (Figure S9A‐B, Supporting Information). The gene discussed is FASN; the disease is Norrie disease.