For instance, ALKBH3‐mediated SP100 demethylation has been implicated in tumorigenesis in ocular melanoma, as determined by both in vitro and in vivo experiments.[13] Moreover, few studies have mentioned that METTL3, a canonical writer protein for m6A methylation, plays a pathogenic role in other fibrotic diseases. This evidence concerns the gene ALKBH3 and ocular melanoma.