We found that the protein levels of PLOD2, CDC20, and HDGF were significantly upregulated in the tumor samples of patients with HCC; the protein levels of PFN2, TALDO1, and FTCD were significantly downregulated in the tumor samples; whereas CCT5 showed no difference (Fig. 8A–G). This evidence concerns the gene TALDO1 and hepatocellular carcinoma.