Specifically, it has been reported that autophagy can regulate the expression of immune checkpoint molecules such as PD-L1, which can suppress the activity of cytotoxic T cells and facilitate immune escape.30 Given that ELAVL1 and LncRNA NEAT1 were found to regulate autophagy in our study, as its overexpression significantly increased the expression of beclin1, an autophagy-related gene, it is conceivable that this autophagy-mediated regulation could influence the expression of immune checkpoint molecules and impact immune evasion mechanisms in endometrial cancer. The gene discussed is NEAT1; the disease is endometrial cancer.