Kidney expression of Lcn2 in injured kidneys originates mainly from the distal tubules and is upregulated particularly in response to toxic or ischemic injuries (Schrezenmeier et al., 2017), while Kim‐1 is upregulated especially during ischemic acute tubular necrosis, and to a lesser degree in other kidney diseases (Han et al., 2002). This evidence concerns the gene LCN2 and kidney disorder.