NPHS1 and colitis: found increased serum creatinine, myeloperoxidase activity, proinflammatory cytokine expression and dilatation of tubules in kidney tissue following DSS colitis (Ranganathan, Jayakumar, Manicassamy, & Ramesh, 2013; Ranganathan, Jayakumar, Santhakumar, & Ramesh, 2013), while Chang and colleagues reported aberrations in the expression of several critical podocyte proteins, synaptopodin, nephrin, and podocalyxin, as well as different collagens around glomeruli (Chang et al., 2019).